Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.55 |
| ▸ | APEX1 | P27695 | 3/20 | 0.55 |
| ▸ | APAF1 | O14727 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.55 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.55 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10490128 | 1.00 | PTGS1 (0.59) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10490127 | 1.00 | PTGS1 (0.59) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10490197 | 1.00 | PTGS1 (0.59) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10792889 | 1.00 | PTGS1 (0.59) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10792895 | 1.00 | PTGS1 (0.59) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10797281 | 0.94 | PTGS1 (0.67) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10796262 | 0.94 | PTGS1 (0.67) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10797276 | 0.94 | PTGS1 (0.67) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10796614 | 0.94 | PTGS1 (0.67) | PTGS1ABCB11PDE4DTDP1APEX1 | |
| SCHEMBL10796609 | 0.94 | PTGS1 (0.67) | PTGS1ABCB11PDE4DTDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4708955-A | ANTIBACTERIALS | BRISTOL-MYERS COMPANY (US) | 1987-11-24 | — | — | US | claimed |
| US-4874856-A | ANTIBIOTICS | BRISTOL-MYERS COMPANY (US) | 1989-10-17 | — | — | US | disclosed |
| EP-0304036-A2 | 3-(substituted)propenyl-7-(aminothiazolylacetamido)ceph-3-em-4-carboxylic acids and esters thereof | Bristol-Myers Squibb Company (US) | 1989-02-22 | — | — | EP | disclosed |
| US-4708955-A | ANTIBACTERIALS | BRISTOL-MYERS COMPANY (US) | 1987-11-24 | — | — | US | disclosed |