Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.38 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11913313 | 0.81 | TDP1 (0.44) | TSHRTP53TDP1PPARDCA12 | |
| SCHEMBL246310 | 0.81 | TSHR (0.50) | TSHRTP53TDP1PPARDBTN3A1 | |
| SCHEMBL12958889 | 0.76 | TSHR (0.42) | TSHRTP53TDP1PPARDCA12 | |
| SCHEMBL15460372 | 0.74 | TP53 (0.42) | TSHRTP53TDP1PPARDCA12 | |
| SCHEMBL10389565 | 0.74 | TSHR (0.40) | TSHRTP53TDP1PPARDCA12 | |
| SCHEMBL12405369 | 0.73 | POLB (0.40) | TSHRTP53TDP1PPARDCA12 | |
| SCHEMBL18052649 | 0.73 | TSHR (0.39) | TSHRTP53TDP1PPARDCA12 | |
| SCHEMBL4402992 | 0.73 | MGAM (0.46) | TSHRTP53TDP1PPARD | |
| SCHEMBL17933674 | 0.73 | TSHR (0.34) | TSHRTP53TDP1PPARDCA12 | |
| SCHEMBL8764678 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4859795-A | Ethylenically unsaturated phosphinic acid and thiophosphinic acid isocyanates and isothiocyanates, and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |
| US-4859562-A | Photosensitive mixture and photosensitive recording material produced therefrom with polymeric compound which is reaction product of unsaturated (thio)phosphinic acid iso(thio)cyanate and active hydrogen containing compound | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-22 | — | — | US | disclosed |