Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10492006 | 0.88 | KMT2A (0.60) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL10577996 | 0.84 | KMT2A (0.63) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL13342832 | 0.84 | KMT2A (0.63) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL3690641 | 0.82 | KMT2A (0.54) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL17443396 | 0.82 | KMT2A (0.54) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL3215701 | 0.79 | KMT2A (0.51) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL17595116 | 0.79 | KMT2A (0.56) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL6937775 | 0.78 | KMT2A (0.72) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL3201408 | 0.77 | ENPP1 (0.50) | KMT2AMEN1GAAESR1ESR2 | |
| SCHEMBL22806503 | 0.75 | KMT2A (0.47) | KMT2AMEN1GAAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4826635-A | MICROBIOCIDES | THE UNIVERSITY OF AKRON (US) | 1989-05-02 | — | — | US | disclosed |