Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL1053135 | 0.97 | TSHR (0.35) | TSHRMEN1KMT2ACYP3A4TDP1 | |
| Bicarbonate SCHEMBL21331675 | 0.89 | TSHR (0.39) | TSHRMEN1KMT2ACYP3A4TDP1 | |
| Oxalic Acid SCHEMBL1049232 | 0.89 | TSHR (0.39) | TSHRMEN1KMT2ACYP3A4TDP1 | |
| Bicarbonate SCHEMBL6365374 | 0.86 | TSHR (0.38) | TSHRMEN1KMT2ACYP3A4TDP1 | |
| Oxalic Acid SCHEMBL1053134 | 0.86 | TSHR (0.38) | TSHRMEN1KMT2ACYP3A4TDP1 | |
| Bicarbonate SCHEMBL7973279 | 0.84 | TSHR (0.37) | TSHRMEN1KMT2ACYP3A4TDP1 | |
| Bicarbonate SCHEMBL6365370 | 0.83 | TSHR (0.39) | TSHRMEN1KMT2ACYP3A4TDP1 | |
| Acetic Acid SCHEMBL15209392 | 0.83 | CA1 (0.47) | TSHRMEN1KMT2ACYP3A4TDP1 | |
| Acetic Acid SCHEMBL16209053 | 0.81 | CA1 (0.44) | TSHRMEN1KMT2ACYP3A4TDP1 | |
| Oxalic Acid SCHEMBL30984434 | 0.78 | KDM4E (0.37) | TSHRMEN1KMT2ACYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7867471-B2 | Process for preparing advanced ceramic powders using onium dicarboxylates | SACHEM, INC. (US) | 2011-01-11 | — | — | US | disclosed |
| US-20090250850-A1 | PROCESS FOR PREPARING ADVANCED CERAMIC POWDERS USING ONIUM DICARBOXYLATES | SACHEM, INC. | 2009-10-08 | — | — | US | disclosed |