Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.41 |
| ▸ | TACR2 | P21452 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10492813 | 1.00 | HTR2A (0.49) | HTR2AKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL10492596 | 1.00 | HTR2A (0.49) | HTR2AKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL10492688 | 1.00 | HTR2A (0.49) | HTR2AKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL10492542 | 1.00 | HTR2A (0.49) | HTR2AKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL10492498 | 1.00 | HTR2A (0.49) | HTR2AKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL10492695 | 0.99 | HTR2A (0.46) | HTR2AKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL10492484 | 0.94 | SKP2 (0.44) | HTR2AKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL10492568 | 0.88 | GFER (0.35) | HTR2AKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL10492551 | 0.88 | MAOB (0.36) | HTR2AKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL27496712 | 0.84 | HTR2A (0.59) | HTR2AKDM4EALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4868225-A | STERICALLY HINDERED META-PHENYLENEDIAMINE CHAIN EXTENDER FOR POLYURETHANES | THE DOW CHEMICAL COMPANY (US) | 1989-09-19 | — | — | US | disclosed |
| US-4866208-A | CURING AGENT FOR EPOXY RESINS; EXTENDERS FOR POLYUREA-URETHANE COPOLYMERS | THE DOW CHEMICAL COMPANY (US) | 1989-09-12 | — | — | US | disclosed |
| US-4792623-A | CURING AGENT, EXTENDER | THE DOW CHEMICAL COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0082258-B1 | SUBSTITUTED M-PHENYLENEDIAMINES | THE DOW CHEMICAL COMPANY (US) | 1986-02-19 | — | — | EP | disclosed |
| EP-0082258-A1 | Substituted m-phenylenediamines | THE DOW CHEMICAL COMPANY (US) | 1983-06-29 | — | — | EP | disclosed |