Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CCKBR | P32239 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.41 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.41 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10493146 | 0.95 | MAPT (0.40) | MEN1KMT2ACCKBRLMNAMAPT | |
| SCHEMBL10635119 | 0.91 | MEN1 (0.39) | MEN1KMT2ACCKBRLMNAMAPT | |
| SCHEMBL10493067 | 0.90 | MEN1 (0.48) | MEN1KMT2ACCKBRLMNAMAPT | |
| SCHEMBL10493246 | 0.88 | MEN1 (0.46) | MEN1KMT2ACCKBRLMNAMAPT | |
| SCHEMBL10493112 | 0.87 | MEN1 (0.46) | MEN1KMT2ACCKBRLMNAMAPT | |
| SCHEMBL10492989 | 0.86 | MAPT (0.49) | MEN1KMT2ACCKBRLMNAMAPT | |
| SCHEMBL11156752 | 0.86 | MAPT (0.49) | MEN1KMT2ACCKBRLMNAMAPT | |
| SCHEMBL10493190 | 0.86 | MAPT (0.37) | MEN1KMT2ACCKBRLMNAMAPT | |
| SCHEMBL10996886 | 0.84 | MEN1 (0.38) | MEN1KMT2ACCKBRLMNAMAPT | |
| SCHEMBL10809228 | 0.83 | MEN1 (0.38) | MEN1KMT2ACCKBRLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4877783-A | β-lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1989-10-31 | — | — | US | disclosed |
| EP-0071395-B1 | BETA-LACTAM ANTIBACTERIAL AGENTS | BEECHAM GROUP PLC (GB) | 1988-08-10 | — | — | EP | disclosed |
| US-4609652-A | FORMAMIDYL DERIVATIVES OF AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP P.L.C. (GB) | 1986-09-02 | — | — | US | disclosed |
| US-4539149-A | β-Lactam antibacterial agents | BEECHAM GROUP P.L.C. (GB) | 1985-09-03 | — | — | US | disclosed |
| EP-0071395-A1 | Beta-lactam antibacterial agents | BEECHAM GROUP PLC (GB) | 1983-02-09 | — | — | EP | disclosed |