SCHEMBL10495366

SCHEMBL10495366

NC(C=O)CCCC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18297988 1.00
SCHEMBL20980423 0.90 TSHR (0.42)
SCHEMBL2610603 0.83
SCHEMBL886898 0.83
SCHEMBL13368624 0.83
SCHEMBL11778128 0.83 TSHR (0.31)
SCHEMBL7419522 0.78
SCHEMBL127505 0.76 SLC6A2 (0.31)
SCHEMBL1044479 0.76
SCHEMBL8235057 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4533730-A BACTERICIDES SHIONOGI & CO., LTD. (JP) 1985-08-06 US claimed
US-4478997-A 1-Oxadethiacepham compounds SHIONOGI & CO., LTD. (JP) 1984-10-23 US claimed
US-4443598-A ANTIBIOTICS AND INTERMEDIATES SHIONOGI & CO., LTD. (JP) 1984-04-17 US claimed
US-4232151-A ANTIBIOTICS SHIONOGI & CO., LTD. (JP) 1980-11-04 US claimed
US-4081443-A Penicillin oxides SHIONOGI & CO., LTD. (JA) 1978-03-28 US claimed
US-4066641-A METHOD FOR CYCLIZATION TO GIVE CEPHEM RING HAMASHIMA YOSHIO 1978-01-03 US claimed
US-4013650-A PROCESS FOR THE MANUFACTURE OF 3-METHYLENE-CEPHAM COMPOUNDS CIBA-GEIGY CORPORATION (US) 1977-03-22 US claimed
CN-115932131-A Enrichment and identification method of carbonylation protein in muscle tissue 南京农业大学 2023-04-07 CN disclosed
CN-114401947-A Radiolabeled compounds targeting prostate specific membrane antigen 省卫生服务机构 2022-04-26 CN disclosed
CN-105745327-A High-yield route for producing compounds from renewable resources 兹莫克姆有限公司 2016-07-06 CN disclosed
CN-101432427-B Method for identifying useful protein derived from brewery yeast SUNTORY LTD 2012-05-09 CN disclosed
CN-101631861-A As the miR-16 regulatory gene and the approach for the treatment of the target of intervening ASURAGEN INC 2010-01-20 CN disclosed
CN-101627121-A As the miRNA regulatory gene and the path for the treatment of the target of intervening ASURAGEN INC 2010-01-13 CN disclosed
US-3987039-A ANTIBACTERIAL SHIONOGI & CO., LTD. (JA) 1976-10-19 US disclosed
US-3980644-A EXTRACTION WITH CYCLOHEXANONE ELI LILLY AND COMPANY (US) 1976-09-14 US disclosed
US-3960844-A Preparation of 6-acylamino-2-methyl-2-halomethyl penams ELI LILLY AND COMPANY (US) 1976-06-01 US disclosed
US-3956287-A BACTERICIDES RICHARDSON-MERRELL INC. (US) 1976-05-11 US disclosed
US-3956288-A 7-[(2,4-Dioxo-1-pyrimidinyl)acylamino]cephalosporin derivatives RICHARDSON-MERRELL INC. (US) 1976-05-11 US disclosed
US-3953436-A 3,4-Dicarboxycephalosporins and derivatives ELI LILLY AND COMPANY (US) 1976-04-27 US disclosed
US-3932393-A 3-Methylenecephalosporins and process for production thereof ELI LILLY AND COMPANY (US) 1976-01-13 US disclosed