SCHEMBL1049600

SCHEMBL1049600

CC1=Cc2c(-c3ccc(C)cc3)cccc2C1[Zr](C)(C)(C1C(C)=Cc2c(-c3ccc(C)cc3)cccc21)[SiH](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60641 0.90 PDCD1 (0.31)
SCHEMBL1047384 0.87 BRD4 (0.33)
SCHEMBL6065479 0.87 EDNRB (0.33)
SCHEMBL6065061 0.86 BACE1 (0.32)
SCHEMBL141357 0.85
SCHEMBL5359556 0.83 GSTP1 (0.35)
SCHEMBL7648704 0.83 EDNRB (0.31)
SCHEMBL1050872 0.82
Hydrochloric Acid SCHEMBL5952381 0.82 EDNRB (0.30)
SCHEMBL22301297 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120178617-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2012-07-12 US claimed
US-8163854-B2 Preparation of supported silyl-capped silica-bound anion activators and associated catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-04-24 US claimed
EP-1799726-B1 TRIALKYLALUMINUM TREATED SUPPORTS EXXONMOBIL CHEM PATENTS INC (US) 2011-07-13 EP claimed
US-20110015357-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2011-01-20 US claimed
US-7385015-B2 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-06-10 US claimed
US-20060079394-A1 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. 2006-04-13 US claimed
US-20050148743-A1 polymerization catalyst systems comprising an ion-exchange layered silicate, an organoaluminum compound, and a heterocyclic compound EXXONMOBIL CHEMICAL PATENTS INC. 2005-07-07 US claimed
US-10676547-B2 Aluminum alkyls with pendant olefins on clays EXXONMOBIL CHEMICAL PATENTS INC. (US) 2020-06-09 US disclosed
US-20180201700-A1 Aluminum Alkyls with Pendant Olefins on Clays EXXONMOBIL CHEMICAL PATENTS INC. 2018-07-19 US disclosed
EP-1709085-B1 SUPPORTED ACTIVATOR FOR POLYMERISATION CATALYST EXXONMOBIL CHEM PATENTS INC (US) 2013-03-20 EP disclosed
US-20120178617-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2012-07-12 US disclosed
US-8163854-B2 Preparation of supported silyl-capped silica-bound anion activators and associated catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-04-24 US disclosed
EP-1799726-B1 TRIALKYLALUMINUM TREATED SUPPORTS EXXONMOBIL CHEM PATENTS INC (US) 2011-07-13 EP disclosed
US-7847038-B2 Preparation of supported silyl-capped silica-bound anion activators and associated catalysts EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-12-07 US disclosed
US-20090018290-A1 Preparation of Supported Silyl-Capped Silica-Bound Anion Activators and Associated Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2009-01-15 US disclosed
US-7385015-B2 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-06-10 US disclosed
US-7220695-B2 Supported activator EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-22 US disclosed
US-7101940-B2 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins BASELL POLYOLEFINE GMBH (DE) 2006-09-05 US disclosed
US-20060079394-A1 Trialkylaluminum treated supports EXXONMOBIL CHEMICAL PATENTS INC. 2006-04-13 US disclosed
US-20030013913-A1 Chemical compound, method for the production thereof and its use in catalyst systems for producing polyolefins EQUISTAR CHEMICALS, LP 2003-01-16 US disclosed