Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10486602 | 0.89 | KDM4E (0.47) | ALDH1A1ESR1TSHRTDP1HPGD | |
| SCHEMBL9823900 | 0.82 | KMT2A (0.44) | ALDH1A1HPGDMEN1MAPTKMT2A | |
| SCHEMBL10496181 | 0.82 | HPGD (0.42) | ALDH1A1TSHRTDP1HPGDMEN1 | |
| SCHEMBL10455068 | 0.79 | TSHR (0.50) | ALDH1A1TSHRTDP1HPGDMEN1 | |
| SCHEMBL10455069 | 0.79 | TSHR (0.50) | ALDH1A1TSHRTDP1HPGDMEN1 | |
| SCHEMBL10387518 | 0.76 | TSHR (0.53) | ALDH1A1ESR1CHRM1TSHRSLC6A2 | |
| SCHEMBL2656460 | 0.75 | HPGD (0.56) | ALDH1A1TSHRTDP1HPGDMEN1 | |
| SCHEMBL9572368 | 0.75 | CYP3A4 (0.46) | ALDH1A1ESR1CHRM1TSHRSLC6A2 | |
| SCHEMBL4776721 | 0.74 | KDM4E (0.50) | ALDH1A1ESR1TSHRTDP1HPGD | |
| SCHEMBL28252097 | 0.73 | SMN1; SMN2 (0.63) | ALDH1A1TSHRTDP1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4803273-A | HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1989-02-07 | — | — | US | disclosed |
| US-4655819-A | Quinoxalinyloxy phenoxy proprionic acid derivatives as selective herbicides | ICI AUSTRALIA LIMITED (AU) | 1987-04-07 | — | — | US | disclosed |
| EP-0060607-B1 | 2-(2-HALO-4-(6-HALOQUINOXALIN-2-YLOXY)PHENOXY)PROPIONATES, PROCESS FOR THEIR SYNTHESIS, HERBICIDAL COMPOSITIONS CONTAINING THEM AND THEIR USE AS HERBICIDES | ICI AUSTRALIA LIMITED (AU) | 1985-08-28 | — | — | EP | disclosed |
| EP-0060607-A1 | 2-(2-halo-4-(6-haloquinoxalin-2-yloxy)phenoxy)propionates, process for their synthesis, herbicidal compositions containing them and their use as herbicides | ICI AUSTRALIA LIMITED (AU) | 1982-09-22 | — | — | EP | disclosed |