Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 6/20 | 0.39 |
| ▸ | ADH1B | P00325 | 2/20 | 0.39 |
| ▸ | ADH1C | P00326 | 2/20 | 0.39 |
| ▸ | ADH1A | P07327 | 2/20 | 0.39 |
| ▸ | ADH4 | P08319 | 2/20 | 0.39 |
| ▸ | ADH7 | P40394 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27280487 | 0.92 | TSHR (0.52) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL27280491 | 0.91 | TSHR (0.46) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL13955421 | 0.86 | ANPEP (0.49) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL17920167 | 0.86 | ANPEP (0.49) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL6285010 | 0.83 | TSHR (0.56) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL14469367 | 0.83 | TSHR (0.56) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL6280015 | 0.83 | TSHR (0.56) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL19636552 | 0.83 | TSHR (0.56) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL9037647 | 0.83 | TSHR (0.50) | TSHRALDH1A1S1PR2S1PR4S1PR1 | |
| SCHEMBL6285476 | 0.83 | TSHR (0.56) | TSHRALDH1A1S1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4798897-A | (AMINOALKYL)AMINOSULFONYL-SUBSTITUTED CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1989-01-17 | — | — | US | disclosed |