Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CHAT | P28329 | 5/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10496696 | 1.00 | PTGS1 (0.48) | PTGS1PTGS2CHATTP53MTNR1A | |
| SCHEMBL10496551 | 1.00 | PTGS1 (0.48) | PTGS1PTGS2CHATTP53MTNR1A | |
| Hydrochloric Acid SCHEMBL10496789 | 0.98 | PTGS1 (0.47) | PTGS1PTGS2CHATTP53MTNR1A | |
| Hydrochloric Acid SCHEMBL10496779 | 0.98 | PTGS1 (0.47) | PTGS1PTGS2CHATTP53MTNR1A | |
| SCHEMBL318014 | 0.84 | CHAT (0.49) | PTGS1PTGS2CHATMTNR1AMTNR1B | |
| SCHEMBL318015 | 0.84 | CHAT (0.49) | PTGS1PTGS2CHATMTNR1AMTNR1B | |
| SCHEMBL29673969 | 0.84 | CHAT (0.49) | PTGS1PTGS2CHATMTNR1AMTNR1B | |
| SCHEMBL6857678 | 0.82 | CHAT (0.51) | PTGS1PTGS2CHAT | |
| SCHEMBL6857677 | 0.82 | CHAT (0.51) | PTGS1PTGS2CHAT | |
| SCHEMBL9247523 | 0.80 | PTGS1 (0.54) | PTGS1PTGS2CHATTP53MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4839353-A | Anti-ulcer substituted pyridine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-06-13 | — | — | US | disclosed |
| EP-0264883-A2 | Substituted pyridine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1988-04-27 | — | — | EP | disclosed |