Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.52 |
| ▸ | TLR4 | O00206 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499064 | 0.98 | CYSLTR2 (0.52) | CYSLTR2TLR4TLR2PLA2G4BSMPD1 | |
| SCHEMBL9338411 | 0.96 | CYSLTR2 (0.52) | CYSLTR2TLR4TLR2PLA2G4BSMPD1 | |
| SCHEMBL9342737 | 0.96 | CYSLTR2 (0.52) | CYSLTR2TLR4TLR2PLA2G4BSMPD1 | |
| SCHEMBL9338292 | 0.96 | CYSLTR2 (0.52) | CYSLTR2TLR4TLR2PLA2G4BSMPD1 | |
| SCHEMBL9339752 | 0.96 | CYSLTR2 (0.52) | CYSLTR2TLR4TLR2PLA2G4BSMPD1 | |
| SCHEMBL9338557 | 0.96 | CYSLTR2 (0.52) | CYSLTR2TLR4TLR2PLA2G4BSMPD1 | |
| SCHEMBL9342494 | 0.96 | CYSLTR2 (0.52) | CYSLTR2TLR4TLR2PLA2G4BSMPD1 | |
| SCHEMBL9337348 | 0.96 | CYSLTR2 (0.52) | CYSLTR2TLR4TLR2PLA2G4BSMPD1 | |
| SCHEMBL9337916 | 0.96 | CYSLTR2 (0.52) | CYSLTR2TLR4TLR2PLA2G4BSMPD1 | |
| SCHEMBL9342093 | 0.96 | CYSLTR2 (0.52) | CYSLTR2TLR4TLR2PLA2G4BSMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |