Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.68 |
| ▸ | BCHE | P06276 | 13/20 | 0.61 |
| ▸ | ACHE | P22303 | 11/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497687 | 1.00 | ABCG2 (0.68) | ABCG2BCHEACHEKDM4ELMNA | |
| SCHEMBL10498411 | 1.00 | ABCG2 (0.68) | ABCG2BCHEACHEKDM4ELMNA | |
| SCHEMBL10497593 | 1.00 | ABCG2 (0.68) | ABCG2BCHEACHEKDM4ELMNA | |
| SCHEMBL10497150 | 1.00 | ABCG2 (0.68) | ABCG2BCHEACHEKDM4ELMNA | |
| SCHEMBL10497738 | 1.00 | ABCG2 (0.68) | ABCG2BCHEACHEKDM4ELMNA | |
| SCHEMBL10497621 | 1.00 | ABCG2 (0.68) | ABCG2BCHEACHEKDM4ELMNA | |
| SCHEMBL10497732 | 1.00 | ABCG2 (0.68) | ABCG2BCHEACHEKDM4ELMNA | |
| SCHEMBL10498405 | 1.00 | ABCG2 (0.68) | ABCG2BCHEACHEKDM4ELMNA | |
| SCHEMBL10497642 | 0.98 | ABCG2 (0.68) | ABCG2BCHEACHEKDM4ELMNA | |
| SCHEMBL10498819 | 0.98 | ABCG2 (0.68) | ABCG2BCHEACHEKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |