Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.81 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.73 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | MAPT | P10636 | 3/20 | 0.71 |
| ▸ | ATM | Q13315 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.62 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497877 | 1.00 | ABCG2 (0.81) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL10497918 | 0.86 | ABCG2 (0.81) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL10497915 | 0.86 | ABCG2 (0.81) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL2458579 | 0.86 | ABCG2 (1.00) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL2458577 | 0.86 | ABCG2 (1.00) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL5471625 | 0.85 | ABCG2 (1.00) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL31436359 | 0.85 | ABCG2 (1.00) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL5471618 | 0.85 | ABCG2 (1.00) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL8461354 | 0.85 | ABCG2 (0.88) | ABCG2TNFRSF1AMEN1KMT2ALMNA | |
| SCHEMBL8461357 | 0.85 | ABCG2 (0.88) | ABCG2TNFRSF1AMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |