Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7802436 | 0.86 | TSHR (0.76) | TSHRCYP3A4CA9HSD17B10KDM4E | |
| SCHEMBL11686088 | 0.84 | TSHR (0.72) | TSHRCYP3A4CA9HSD17B10KDM4E | |
| SCHEMBL7801334 | 0.83 | TSHR (0.71) | TSHRCYP3A4CA9HSD17B10KDM4E | |
| SCHEMBL21017307 | 0.82 | TSHR (0.69) | TSHRCYP3A4CA9HSD17B10KDM4E | |
| SCHEMBL10497899 | 0.81 | CYP3A4 (0.68) | TSHRCYP3A4CA9KDM4ECREBBP | |
| SCHEMBL23202755 | 0.80 | CYP3A4 (0.67) | TSHRCYP3A4CA9HSD17B10KDM4E | |
| SCHEMBL30350318 | 0.80 | CYP3A4 (0.67) | TSHRCYP3A4CA9HSD17B10KDM4E | |
| SCHEMBL2281556 | 0.79 | KDM4E (0.75) | TSHRCYP3A4CA9KDM4ECREBBP | |
| SCHEMBL11684821 | 0.79 | TSHR (0.65) | TSHRCYP3A4CA9HSD17B10KDM4E | |
| SCHEMBL24651214 | 0.79 | TSHR (0.65) | TSHRCYP3A4HSD17B10KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |