Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497601 | 1.00 | MAOB (0.58) | MAOBMAOACXCL12CYP1B1ABCG2 | |
| SCHEMBL10498629 | 1.00 | MAOB (0.58) | MAOBMAOACXCL12CYP1B1ABCG2 | |
| SCHEMBL10497629 | 1.00 | MAOB (0.58) | MAOBMAOACXCL12CYP1B1ABCG2 | |
| SCHEMBL9337944 | 0.95 | MAOB (0.56) | MAOBMAOACXCL12CYP1B1ABCG2 | |
| SCHEMBL9342202 | 0.95 | MAOB (0.56) | MAOBMAOACXCL12CYP1B1ABCG2 | |
| SCHEMBL9337932 | 0.95 | MAOB (0.56) | MAOBMAOACXCL12CYP1B1ABCG2 | |
| SCHEMBL9342195 | 0.95 | MAOB (0.56) | MAOBMAOACXCL12CYP1B1ABCG2 | |
| SCHEMBL9342016 | 0.87 | MAPT (0.57) | MAOBMAOACXCL12CYP1B1ABCG2 | |
| SCHEMBL9339786 | 0.87 | ABCG2 (0.53) | CXCL12CYP1B1ABCG2MEN1KMT2A | |
| SCHEMBL9339789 | 0.87 | ABCG2 (0.53) | CXCL12CYP1B1ABCG2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |