Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 3/20 | 0.50 |
| ▸ | APP | P05067 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | AGER | Q15109 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11252528 | 0.89 | GAA (0.70) | GAAALDH1A1HTTTHRBMAPT | |
| SCHEMBL10499416 | 0.86 | GAA (0.46) | GAAALDH1A1HTTTHRBAPP | |
| SCHEMBL10498867 | 0.85 | GAA (0.45) | GAAALDH1A1HTTTHRBAPP | |
| SCHEMBL10499055 | 0.85 | GAA (0.45) | GAAALDH1A1HTTTHRBAPP | |
| SCHEMBL10499081 | 0.85 | GAA (0.45) | GAAALDH1A1HTTTHRBAPP | |
| SCHEMBL10499063 | 0.85 | GAA (0.45) | GAAALDH1A1HTTTHRBAPP | |
| SCHEMBL5028293 | 0.81 | GAA (0.61) | GAAALDH1A1HTTTHRBMAPT | |
| SCHEMBL1161861 | 0.79 | APP (0.55) | GAAALDH1A1THRBAPPL3MBTL1 | |
| SCHEMBL11142878 | 0.79 | GAA (0.59) | GAAALDH1A1HTTTHRBAPP | |
| SCHEMBL2705170 | 0.79 | GAA (0.59) | GAAALDH1A1HTTTHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0262618-A2 | N-(omega)-cyanoalkyl)aminophenols, and their preparation | STERLING DRUG INC. (US) | 1988-04-06 | — | — | EP | disclosed |