Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10499402 | 0.81 | CHRM2 (0.49) | MGLLKMT2AMEN1 | |
| SCHEMBL4257353 | 0.80 | MAPT (0.59) | GAAALDH1A1MAPTHSP90AA1LMNA | |
| SCHEMBL8908646 | 0.79 | GAA (0.51) | GAAALDH1A1MAPTHSP90AA1MGLL | |
| SCHEMBL15613886 | 0.77 | GAA (0.53) | GAAALDH1A1MAPTHSP90AA1LMNA | |
| SCHEMBL3474585 | 0.77 | PRSS1 (0.46) | GAAALDH1A1 | |
| SCHEMBL10498867 | 0.76 | GAA (0.45) | GAAALDH1A1MAPTHTT | |
| SCHEMBL10499063 | 0.76 | GAA (0.45) | GAAALDH1A1MAPTHTT | |
| SCHEMBL10499081 | 0.76 | GAA (0.45) | GAAALDH1A1MAPTHTT | |
| SCHEMBL10499055 | 0.76 | GAA (0.45) | GAAALDH1A1MAPTHTT | |
| SCHEMBL3411340 | 0.75 | NPC1 (0.58) | GAAALDH1A1MAPTHSP90AA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0262618-A2 | N-(omega)-cyanoalkyl)aminophenols, and their preparation | STERLING DRUG INC. (US) | 1988-04-06 | — | — | EP | disclosed |