Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | CHAT | P28329 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10501381 | 1.00 | KDM4E (0.49) | KDM4EMTNR1AMTNR1BCHATPTGS1 | |
| SCHEMBL6027912 | 0.80 | KDM4E (0.54) | KDM4EMTNR1AMTNR1BCHATPTGS1 | |
| SCHEMBL10887692 | 0.80 | KDM4E (0.44) | KDM4EMTNR1AMTNR1BCHATPTGS1 | |
| SCHEMBL10887689 | 0.80 | KDM4E (0.44) | KDM4EMTNR1AMTNR1BCHATPTGS1 | |
| SCHEMBL28257775 | 0.79 | KDM4E (0.57) | KDM4EMTNR1AMTNR1BCHATPTGS1 | |
| SCHEMBL9997658 | 0.77 | KDM4E (0.49) | KDM4EMTNR1AMTNR1BHDAC8HDAC6 | |
| SCHEMBL9997661 | 0.77 | KDM4E (0.49) | KDM4EMTNR1AMTNR1BHDAC8HDAC6 | |
| SCHEMBL31172233 | 0.77 | KDM4E (0.51) | KDM4EMTNR1AMTNR1BCHATPTGS1 | |
| SCHEMBL6001348 | 0.77 | KDM4E (0.51) | KDM4EMTNR1AMTNR1BCHATPTGS1 | |
| SCHEMBL29008891 | 0.76 | KDM4E (0.46) | KDM4EMTNR1AMTNR1BCHATPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863917-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-05 | — | — | US | disclosed |
| US-4829063-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-05-09 | — | — | US | disclosed |
| US-4804406-A | PLANT FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| US-4804659-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| US-4721786-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1988-01-26 | — | — | US | disclosed |