Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.74 |
| ▸ | RAB9A | P51151 | 4/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | RARB | P10826 | 6/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | RARA | P10276 | 1/20 | 0.51 |
| ▸ | MTOR | P42345 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10500496 | 1.00 | MAPT (0.74) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL10500673 | 1.00 | MAPT (0.74) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL10501426 | 0.97 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL10501582 | 0.97 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9723153 | 0.97 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9850122 | 0.97 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9850179 | 0.97 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9850258 | 0.97 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL10482122 | 0.97 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL9850155 | 0.97 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0160790-B1 | BIPYRIMIDINYL DERIVATIVES AND LIQUID CRYSTAL COMPOSITIONS CONTAINING THEM | Chisso Corporation (JP) | 1989-08-16 | — | — | EP | disclosed |
| US-4609485-A | LIQUID CRYSTALS | CHISSO CORPORATION (JP) | 1986-09-02 | — | — | US | disclosed |
| EP-0160790-A2 | Bipyrimidinyl derivatives and liquid crystal compositions containing them | Chisso Corporation (JP) | 1985-11-13 | — | — | EP | disclosed |