Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9556497 | 1.00 | CYP11B1 (0.37) | CYP11B1CYP11B2ARGRM2KDM1A | |
| SCHEMBL10776512 | 1.00 | CYP11B1 (0.37) | CYP11B1CYP11B2ARGRM2KDM1A | |
| SCHEMBL9556494 | 1.00 | CYP11B1 (0.37) | CYP11B1CYP11B2ARGRM2KDM1A | |
| SCHEMBL9556121 | 0.99 | CYP11B1 (0.37) | CYP11B1CYP11B2ARGRM2 | |
| SCHEMBL10501267 | 0.99 | CYP11B1 (0.37) | CYP11B1CYP11B2ARGRM2 | |
| SCHEMBL9556119 | 0.99 | CYP11B1 (0.37) | CYP11B1CYP11B2ARGRM2 | |
| SCHEMBL9556346 | 0.99 | CYP11B1 (0.37) | CYP11B1CYP11B2ARGRM2 | |
| SCHEMBL10508200 | 0.99 | CYP11B1 (0.37) | CYP11B1CYP11B2ARGRM2 | |
| SCHEMBL9556180 | 0.99 | CYP11B1 (0.37) | CYP11B1CYP11B2ARGRM2 | |
| SCHEMBL10501753 | 0.99 | CYP11B1 (0.37) | CYP11B1CYP11B2ARGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0154840-B1 | LIQUID CRYSTAL COMPOUNDS | MERCK PATENT GmbH (DE) | 1989-01-25 | — | — | EP | disclosed |
| US-4704227-A | DERIVATIVES OF 1,3-DIOXANE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1987-11-03 | — | — | US | disclosed |
| EP-0205503-A1 | LIQUID CRYSTALLINE PHASE. | MERCK PATENT GMBH (DE) | 1986-12-30 | — | — | EP | disclosed |
| WO-1986003769-A1 | LIQUID CRYSTALLINE PHASE | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1986-07-03 | — | — | WO | disclosed |
| EP-0154840-A2 | Liquid crystal compounds | MERCK PATENT GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |