Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15524338 | 0.85 | MEN1 (0.50) | ALDH1A1TSHRMAPK1MEN1KMT2A | |
| SCHEMBL3644301 | 0.84 | TDP1 (0.30) | TDP1 | |
| SCHEMBL27754438 | 0.83 | HSD17B10 (0.44) | TDP1TSHR | |
| SCHEMBL23817271 | 0.80 | — | — | |
| SCHEMBL7540597 | 0.78 | — | — | |
| SCHEMBL26641882 | 0.77 | HSD17B10 (0.39) | TDP1 | |
| SCHEMBL12285378 | 0.77 | — | — | |
| SCHEMBL765642 | 0.77 | — | — | |
| SCHEMBL17656329 | 0.77 | — | — | |
| SCHEMBL28030709 | 0.75 | MEN1 (0.44) | ALDH1A1TSHRMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451974-A2 | OLIGONUCLEOTIDE-BASED COMPOUNDS AS INHIBITORS OF TOLL-LIKE RECEPTORS | Idera Pharmaceuticals, Inc. (US) | 2012-05-16 | — | — | EP | claimed |
| WO-2011005942-A2 | OLIGONUCLEOTIDE-BASED COMPOUNDS AS INHIBITORS OF TOLL-LIKE RECEPTORS | IDERA PHARMACEUTICALS, INC. (US) | 2011-01-13 | — | — | WO | claimed |
| EP-2179061-A2 | TOLL LIKE RECEPTOR MODULATORS | Idera Pharmaceuticals, Inc. (US) | 2010-04-28 | — | — | EP | claimed |
| JP-2009533348-A | — | — | 2009-09-17 | — | — | JP | claimed |
| WO-2009023819-A2 | TOLL LIKE RECEPTOR MODULATORS | IDERA PHARMACEUTICALS, INC. (US) | 2009-02-19 | — | — | WO | claimed |
| EP-2021008-A2 | STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS FOR TLR7 AND TLR8 | Idera Pharmaceuticals, Inc. (US) | 2009-02-11 | — | — | EP | claimed |
| WO-2007117686-A2 | STABILIZED IMMUNE MODULATORY RNA (SIMRA) COMPOUNDS FOR TLR7 AND TLR8 | IDERA PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | claimed |
| US-20160022826-A1 | CARBOHYDRATE-MODIFIED GLYCOPROTEINS AND USES THEREOF | LUMOS PHARMA, INC. | 2016-01-28 | — | — | US | disclosed |