Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASAH1 | Q13510 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028856 | 0.92 | ASAH1 (0.48) | ASAH1SMN1; SMN2APAF1NPC1ALDH1A1 | |
| SCHEMBL13092517 | 0.86 | ASAH1 (0.66) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL10504808 | 0.81 | ASAH1 (0.47) | ASAH1SMN1; SMN2APAF1NPC1ALDH1A1 | |
| SCHEMBL10504855 | 0.79 | KMT2A (0.53) | ASAH1SMN1; SMN2APAF1NPC1ALDH1A1 | |
| SCHEMBL10503830 | 0.77 | KMT2A (0.65) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL17322551 | 0.76 | EGLN3 (0.51) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL7132708 | 0.75 | ASAH1 (0.55) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL9181106 | 0.74 | TDP1 (0.62) | SMN1; SMN2APAF1NPC1MAPTRAB9A | |
| SCHEMBL6316254 | 0.74 | ASAH1 (0.54) | ASAH1SMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL339546 | 0.74 | ASAH1 (0.46) | ASAH1SMN1; SMN2APAF1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0193307-B1 | PROCESS FOR THE EXTRACTION OF METAL VALUES AND NOVEL METAL EXTRACTANTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-08-09 | — | — | EP | disclosed |
| EP-0193307-A2 | Process for the extraction of metal values and novel metal extractants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-03 | — | — | EP | disclosed |