Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1S | Q13698 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN4A | P35499 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10507069 | 0.91 | CACNA1S (0.44) | CACNA1SCYP3A4TSHRABCB11LMNA | |
| SCHEMBL10600834 | 0.90 | CACNA1S (0.45) | CACNA1SCYP3A4TSHRABCB11LMNA | |
| SCHEMBL10608450 | 0.88 | CACNA1S (0.57) | CACNA1SCYP3A4TSHRABCB11LMNA | |
| SCHEMBL10508705 | 0.85 | CACNA1S (0.40) | CACNA1SALDH1A1FPR1L3MBTL1 | |
| SCHEMBL10506633 | 0.83 | CACNA1S (0.43) | CACNA1SCYP3A4TSHRABCB11LMNA | |
| SCHEMBL10840712 | 0.81 | CACNA1S (0.67) | CACNA1SCYP3A4TSHRABCB11LMNA | |
| SCHEMBL10840717 | 0.81 | CACNA1S (0.67) | CACNA1SCYP3A4TSHRABCB11LMNA | |
| SCHEMBL10840707 | 0.81 | CACNA1S (0.67) | CACNA1SCYP3A4TSHRABCB11LMNA | |
| Bromide SCHEMBL10508180 | 0.80 | CACNA1S (0.66) | CACNA1SCYP3A4TSHRABCB11LMNA | |
| Bromide SCHEMBL10842248 | 0.80 | CACNA1S (0.66) | CACNA1SCYP3A4TSHRABCB11LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0158339-B1 | 1,5-BENZOTHIAZEPHINE DERIVATIVES, PROCESSES FOR PREPARING THE SAME AND PHARMACEUTICAL COMPOSITIONS | Tanabe Seiyaku Co., Ltd. (JP) | 1989-01-18 | — | — | EP | disclosed |