Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10996562 | 0.86 | MAPT (0.50) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL10996566 | 0.86 | MAPT (0.50) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL7620611 | 0.81 | MAPT (0.45) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL9756773 | 0.80 | NPC1 (0.52) | MAPTKMT2AMEN1CES1HPGD | |
| SCHEMBL11433238 | 0.80 | GSK3B (0.53) | MAPTCES1CYP3A4KDM4EALOX15 | |
| SCHEMBL3125298 | 0.80 | MAPT (0.53) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL315304 | 0.78 | MAPT (0.56) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL11070858 | 0.78 | TDP1 (0.61) | MAPTKMT2AMAPK1MEN1TDP1 | |
| SCHEMBL11164619 | 0.77 | HDAC3 (0.60) | MAPTKMT2AMAPK1TDP1CES1 | |
| SCHEMBL8331813 | 0.77 | PDPK1 (0.48) | KMT2AMEN1CES1KDM4EMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300278-A2 | Process for the preparation of 2-substituted pyrroles | BAYER AG (DE) | 1989-01-25 | — | — | EP | disclosed |
| EP-0019089-A1 | 5-Aryl-3-(1'-halogen-1'-methyl)ethyl-pent-4-en-carboxylic acid esters, process for their preparation, and their use for the preparation of 3-(2-arylvinyl)-2,2-dimethyl-cyclopropane-1-carboxylic acid esters | BAYER AG (DE) | 1980-11-26 | — | — | EP | disclosed |
| EP-0018532-A1 | 1-Aryl-4-methyl-penta-1,2-dienes, process for their preparation and their use for the preparation of 3-(2-aryl-vinyl)-2,2-dimethylcyclopropane-1-carboxylates | BAYER AG (DE) | 1980-11-12 | — | — | EP | disclosed |