SCHEMBL10507759

SCHEMBL10507759

COC(=O)COC(=O)Cc1cccc(Oc2ccc(C(F)(F)F)cc2Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 10/20 0.50
HTT P42858 2/20 0.49
POLB P06746 1/20 0.49
FFAR1 O14842 2/20 0.48
ALDH1A1 P00352 2/20 0.47
PPARG P37231 1/20 0.45
PPARD Q03181 1/20 0.45
PPARA Q07869 1/20 0.45
LMNA P02545 1/20 0.45
CYP1A2 P05177 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C19 P33261 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10509965 0.88 FFAR1 (0.51) MRGPRX4FFAR1PPARGPPARDPPARA
SCHEMBL10692331 0.87 MRGPRX4 (0.56) MRGPRX4FFAR1
SCHEMBL10510999 0.85 FFAR1 (0.48) MRGPRX4FFAR1PPARGPPARDPPARA
SCHEMBL10507578 0.82 FFAR1 (0.56) MRGPRX4FFAR1PPARGPPARDPPARA
SCHEMBL10507700 0.82 FFAR1 (0.62) MRGPRX4FFAR1PPARGPPARDPPARA
SCHEMBL11205584 0.82 MRGPRX4 (0.51) MRGPRX4POLBFFAR1PPARGPPARD
SCHEMBL10509502 0.81 MRGPRX4 (0.57) MRGPRX4FFAR1PPARGPPARDPPARA
SCHEMBL10509080 0.81 FFAR1 (0.48) MRGPRX4FFAR1PPARGPPARDPPARA
SCHEMBL11204692 0.81 MRGPRX4 (0.49) MRGPRX4FFAR1PPARGPPARDPPARA
SCHEMBL10512308 0.79 MEN1 (0.60) POLBFFAR1ALDH1A1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161529-B1 2-NITRO-5-(2'-CHLORO-4'TRIFLUOROMETHYLPHENOXY)PHENYLACETIC ESTER, THIOESTER AND AMIDE, PROCESS FOR PREPARATION THEROF, HERBICIDAL COMPOSITION, AND METHOD FOR DESTRUCTION OF UNDESIRABLE WEEDS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1989-07-12 EP disclosed
US-4698094-A 2-nitro-5-(2'chloro-4'trifluoromethylphenoxy)-phenylacetic esters, herbicidal composition, and method for destruction of undesirable weeds ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1987-10-06 US disclosed
EP-0161529-A2 2-nitro-5-(2'-chloro-4'trifluoromethylphenoxy)phenylacetic ester, thioester and amide, process for preparation therof, herbicidal composition, and method for destruction of undesirable weeds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1985-11-21 EP disclosed