⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31687184 | 0.98 | KDR (0.41) | — | |
| SCHEMBL31496664 | 0.98 | KDR (0.41) | — | |
| Hydrochloric Acid SCHEMBL30801293 | 0.98 | KDR (0.41) | — | |
| SCHEMBL29649189 | 0.98 | KDR (0.41) | — | |
| Hydrochloric Acid SCHEMBL30066525 | 0.98 | KDR (0.41) | — | |
| SCHEMBL4948667 | 0.98 | KDR (0.41) | — | |
| SCHEMBL400139 | 0.95 | — | — | |
| Hydrazine SCHEMBL6036676 | 0.93 | DRD4 (0.40) | — | |
| Oxalic Acid SCHEMBL572020 | 0.88 | KDM4E (0.40) | — | |
| SCHEMBL30994991 | 0.83 | TRIM24 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 817 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240317753-A9 | Tricyclic heterocycles | MERCK PATENT GMBH (DE) | 2024-09-26 | — | — | US | claimed |
| CN-115944626-B | Application of small molecular compound in preparation of anti-hypoxia or ischemia reperfusion injury drugs | 桂林医学院附属医院 | 2024-04-19 | — | — | CN | claimed |
| US-20230174538-A1 | Tricyclic heterocycles | MERCK PATENT GMBH (DE) | 2023-06-08 | — | — | US | claimed |
| CN-114456228-A | Substituted glycine-3, 5-difluorophenylalanine peptide derivative and preparation method and application thereof | 山东大学 | 2022-05-10 | — | — | CN | claimed |
| US-20210253562-A1 | ACYLSUFONAMIDE COMPOUNDS USEFUL AS EP3 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2021-08-19 | — | — | US | claimed |
| US-10797249-B2 | Organometallic compound, organic light-emitting device including the organometallic compound, and diagnostic composition including the organometallic compound | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2020-10-06 | — | — | US | claimed |
| WO-2020008317-A1 | ACYLSUFONAMIDE COMPOUNDS USEFUL AS EP3 RECEPTOR ANTAGONISTS | JANSSEN PHARMACEUTICA NV (BE) | 2020-01-09 | — | — | WO | claimed |
| EP-2562294-B1 | PLATING BATH AND METHOD | ROHM & HAAS ELECT MAT (US) | 2019-09-25 | — | — | EP | claimed |
| US-20180342686-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2018-11-29 | — | — | US | claimed |
| EP-2943487-B1 | 5-MEMBERED HETEROARYLS AND THEIR USE AS ANTIVIRAL AGENTS | GILEAD SCIENCES INC (US) | 2016-11-16 | — | — | EP | claimed |
| EP-1505966-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2005-02-16 | — | — | EP | claimed |
| US-20040254158-A1 | Anticoagulants; atherosclerosis; strokes; thrombosis; cardiovascular disorders | BRISTOL-MYERS SQUIBB COMPANY | 2004-12-16 | — | — | US | claimed |
| EP-1478624-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2004-11-24 | — | — | EP | claimed |
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | claimed |
| WO-2003099276-A1 | 1,1-DISUBSTITUTED CYCLOALKYL DERIVATIVES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-12-04 | — | — | WO | claimed |
| WO-2003068743-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-21 | — | — | WO | claimed |
| JP-2002544271-A | — | — | 2002-12-24 | — | — | JP | claimed |
| EP-1177185-A1 | 4, 5, 6, 7-TETRAHYDROINDAZOLE DERIVATIVES AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 2002-02-06 | — | — | EP | claimed |
| WO-2000069846-A1 | 4,5,6,7-TETRAHYDROINDAZOLE DERIVATIVES AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-11-23 | — | — | WO | claimed |
| US-5049181-A | Novel herbicidally active n-phenyl-azoles | CIBA-GEIGY CORPORATION (US) | 1991-09-17 | — | — | US | claimed |