Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 13/20 | 0.86 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.81 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.81 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.81 |
| ▸ | LMNA | P02545 | 1/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.81 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.81 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.81 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.81 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.81 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.81 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14627933 | 0.93 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| SCHEMBL21283696 | 0.93 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| SCHEMBL22079612 | 0.93 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| SCHEMBL23424218 | 0.93 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| SCHEMBL22079590 | 0.93 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| SCHEMBL24170380 | 0.93 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| SCHEMBL22079190 | 0.93 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| SCHEMBL24999603 | 0.93 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| SCHEMBL22152087 | 0.93 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A | |
| SCHEMBL22062319 | 0.93 | GPBAR1 (1.00) | GPBAR1NR1H4ABCB11MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202703-B1 | PHARMACEUTICAL COMPOSITIONS OF THE PRODRUG TYPE, A PROCESS FOR THE PREPARATION THEREOF, A PROCESS FOR THE PREPARATION OF THEM AS PRODRUG FUNCTIONING COMPOUNDS AND COMPOUNDS OBTAINED THEREIN | N.V. Gantax Pharmaceutica (BE) | 1989-08-09 | — | — | EP | claimed |
| EP-0202703-A1 | Pharmaceutical compositions of the prodrug type, a process for the preparation thereof, a process for the preparation of them as prodrug functioning compounds and compounds obtained therein | N.V. Gantax Pharmaceutica (BE) | 1986-11-26 | — | — | EP | claimed |
| US-4863965-A | Ibuprofen acid anhydrides and prodrug pharmaceutical composition containing the same | B.V.B.A. INPHARM (BE) | 1989-09-05 | — | — | US | disclosed |
| EP-0202703-B1 | PHARMACEUTICAL COMPOSITIONS OF THE PRODRUG TYPE, A PROCESS FOR THE PREPARATION THEREOF, A PROCESS FOR THE PREPARATION OF THEM AS PRODRUG FUNCTIONING COMPOUNDS AND COMPOUNDS OBTAINED THEREIN | N.V. Gantax Pharmaceutica (BE) | 1989-08-09 | — | — | EP | disclosed |
| EP-0202703-A1 | Pharmaceutical compositions of the prodrug type, a process for the preparation thereof, a process for the preparation of them as prodrug functioning compounds and compounds obtained therein | N.V. Gantax Pharmaceutica (BE) | 1986-11-26 | — | — | EP | disclosed |