Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 8/20 | 0.35 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10518478 | 0.95 | ACACB (0.37) | ACACBMAPTL3MBTL1GLSLMNA | |
| SCHEMBL10509708 | 0.93 | ACACB (0.36) | ACACBL3MBTL1GLSLMNAHPGD | |
| SCHEMBL10512668 | 0.92 | HRH2 (0.35) | ACACBMAPT | |
| SCHEMBL10513511 | 0.89 | HSD17B10 (0.37) | ACACBLMNA | |
| SCHEMBL10512126 | 0.89 | HSD17B10 (0.37) | ACACBLMNA | |
| SCHEMBL10510144 | 0.89 | HSD17B10 (0.37) | ACACBLMNA | |
| SCHEMBL10511024 | 0.89 | CYP19A1 (0.35) | ACACBLMNA | |
| SCHEMBL9855927 | 0.88 | ACACB (0.42) | ACACBCACNA2D1MAPTRAB9AL3MBTL1 | |
| SCHEMBL9855319 | 0.88 | ACACB (0.42) | ACACBCACNA2D1MAPTRAB9AL3MBTL1 | |
| SCHEMBL9855585 | 0.88 | ACACB (0.42) | ACACBCACNA2D1MAPTRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0306505-A1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES. | MERCK PATENT GMBH (DE) | 1989-03-15 | — | — | EP | disclosed |
| WO-1988007523-A1 | ACETYLENE DERIVATIVES AS COMPONENTS OF LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |