Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8598155 | 0.89 | TSHR (0.48) | TSHRKMT2ARAB9ANPSR1MAPT | |
| SCHEMBL5970046 | 0.87 | TSHR (0.58) | TSHRKMT2ARAB9ANPSR1MAPT | |
| SCHEMBL11751433 | 0.87 | KDM4E (0.53) | TSHRKMT2ARAB9ANPSR1MAPT | |
| SCHEMBL11753672 | 0.87 | KDM4E (0.53) | TSHRKMT2ARAB9ANPSR1MAPT | |
| SCHEMBL11777317 | 0.87 | KDM4E (0.53) | TSHRKMT2ARAB9ANPSR1MAPT | |
| SCHEMBL11747508 | 0.87 | KDM4E (0.53) | TSHRKMT2ARAB9ANPSR1MAPT | |
| SCHEMBL11749159 | 0.87 | KDM4E (0.53) | TSHRKMT2ARAB9ANPSR1MAPT | |
| SCHEMBL11747519 | 0.87 | KDM4E (0.53) | TSHRKMT2ARAB9ANPSR1MAPT | |
| SCHEMBL10513445 | 0.86 | TSHR (0.47) | TSHRKMT2ARAB9ANPSR1MAPT | |
| SCHEMBL10513278 | 0.86 | TSHR (0.47) | TSHRKMT2ARAB9ANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0196153-B1 | PROCESS FOR THE EXTRACTION OF METAL VALUES AND NOVEL METAL EXTRACTANTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-07-26 | — | — | EP | claimed |
| US-4696801-A | Process for the extraction of metal values with bisimidazole metal extractants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-09-29 | — | — | US | claimed |
| EP-0196153-A2 | Process for the extraction of metal values and novel metal extractants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-10-01 | — | — | EP | claimed |
| EP-0196153-B1 | PROCESS FOR THE EXTRACTION OF METAL VALUES AND NOVEL METAL EXTRACTANTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-07-26 | — | — | EP | disclosed |
| US-4822880-A | 1,1'-SUBSTITUTED 2,2'-BIIMIDAZOLE OR BIBENZIMIDAZOLES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-04-18 | — | — | US | disclosed |
| EP-0308438-A1 | Liquid crystal phase containing tolanes. | MERCK PATENT GMBH (DE) | 1989-03-29 | — | — | EP | disclosed |
| WO-1988007514-A1 | TOLANES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-10-06 | — | — | WO | disclosed |
| US-4696801-A | Process for the extraction of metal values with bisimidazole metal extractants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-09-29 | — | — | US | disclosed |
| EP-0196153-A2 | Process for the extraction of metal values and novel metal extractants | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-10-01 | — | — | EP | disclosed |