Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 20/20 | 0.71 |
| ▸ | HTR2C | P28335 | 20/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.71 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | HTR7 | P34969 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | HTR6 | P50406 | 2/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2681226 | 0.99 | HTR2A (0.72) | HTR2AHTR2CSLC6A4KCNH2CYP2D6 | |
| SCHEMBL1077992 | 0.94 | HTR2A (0.64) | HTR2AHTR2CSLC6A4KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2682993 | 0.94 | HTR2A (0.65) | HTR2AHTR2CSLC6A4KCNH2CYP2D6 | |
| SCHEMBL1051134 | 0.93 | HTR2A (0.71) | HTR2AHTR2CSLC6A4KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2682641 | 0.92 | HTR2A (0.72) | HTR2AHTR2CSLC6A4KCNH2CYP2D6 | |
| SCHEMBL1078584 | 0.92 | HTR2A (0.72) | HTR2AHTR2CSLC6A4KCNH2HTR1A | |
| Hydrochloric Acid SCHEMBL2682777 | 0.92 | HTR2A (0.72) | HTR2AHTR2CSLC6A4KCNH2HTR1A | |
| SCHEMBL2682465 | 0.89 | HTR2A (0.63) | HTR2AHTR2CSLC6A4KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2682550 | 0.89 | HTR2A (0.64) | HTR2AHTR2CSLC6A4KCNH2CYP2D6 | |
| SCHEMBL2683114 | 0.88 | HTR2A (0.70) | HTR2AHTR2CSLC6A4KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8835436-B2 | Arylpiperazine-containing imidazole 4-carboxamide derivatives and pharmaceutical composition comprising same | GREEN CROSS CORPORATION (KR) | 2014-09-16 | — | — | US | claimed |
| WO-2011005052-A2 | NOVEL ARYLPIPERAZINE-CONTAINING IMIDAZOLE 4-CARBOXAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | GREEN GROSS CORPORATION (KR) | 2011-01-13 | — | — | WO | disclosed |