Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.73 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.73 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.73 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.73 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.73 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.73 |
| ▸ | DRD1 | P21728 | 1/20 | 0.73 |
| ▸ | DRD5 | P21918 | 1/20 | 0.73 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10518059 | 0.98 | CHRM2 (0.69) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL10518480 | 0.94 | CHRM2 (0.64) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL10515620 | 0.94 | CHRM2 (0.65) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL10515020 | 0.90 | — | — | |
| SCHEMBL10516489 | 0.90 | CHRM2 (0.70) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL10516759 | 0.89 | CHRM2 (0.80) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL10569796 | 0.89 | CHRM2 (0.67) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL9824570 | 0.88 | CHRM2 (0.66) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL10515636 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL9676447 | 0.85 | CHRM2 (0.70) | CHRM2CHRM4CHRM1CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345629-A2 | Condensed diazepinones, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1989-12-13 | — | — | EP | disclosed |