⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15022 | 0.87 | — | — | |
| SCHEMBL679120 | 0.87 | — | — | |
| Ethylene SCHEMBL20454806 | 0.80 | — | — | |
| SCHEMBL4450502 | 0.80 | — | — | |
| SCHEMBL4440883 | 0.80 | — | — | |
| SCHEMBL1472728 | 0.80 | — | — | |
| SCHEMBL4448885 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL9726137 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL3791290 | 0.80 | — | — | |
| SCHEMBL4439080 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2216318-B1 | Resolvins: Biotemplates for therapeutic interventions | BRIGHAM & WOMENS HOSPITAL (US) | 2018-10-10 | — | — | EP | disclosed |
| US-8933270-B2 | Use of docasatrienes, resolvins, and their stable analogs in the treatment of airway diseases and asthma | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140179630-A1 | USE OF DOCASATRIENES, RESOLVINS, AND THEIR STABLE ANALOGS IN THE TREATMENT OF AIRWAY DISEASES AND ASTHMA | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2014-06-26 | — | — | US | disclosed |
| US-8569542-B2 | Use of docosatrienes, resolvins, and their stable analogs in the treatment of airway diseases and asthma | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2013-10-29 | — | — | US | disclosed |
| US-20130217771-A1 | RESOLVINS: BIOEMPLATES FOR NOVEL THERAPEUTIC INTERVENTIONS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2013-08-22 | — | — | US | disclosed |
| US-20120264713-A1 | USE OF DOCOSATRIENES, RESOLVINS, AND THEIR STABLE ANALOGS IN THE TREATMENT OF AIRWAY DISEASES AND ASTHMA | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2012-10-18 | — | — | US | disclosed |
| US-7872152-B2 | Di- and tri-hydroxy derivatives of eicosapentaenoic acid and docosahexaenoic acid coadministered with a cyclooxygenase-2 inhibitor; antiinflammatory agents | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2011-01-18 | — | — | US | disclosed |
| EP-2216318-A2 | Resolvins: Biotemplates for therapeutic interventions | BRIGHAM AND WOMEN'S HOSPITAL (US) | 2010-08-11 | — | — | EP | disclosed |
| US-7759395-B2 | Di- and tri-hydroxy derivatives of eicosapentaenoic acid and docosahexaenoic acid coadministered with a cyclooxygenase-2 inhibitor; antiinflammatory agents | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2010-07-20 | — | — | US | disclosed |
| US-20100016432-A1 | RESOLVINS: BIOTEMPLATES FOR NOVEL THERAPEUTIC INTERVENTIONS | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2010-01-21 | — | — | US | disclosed |
| US-20060293288-A1 | Use of resolvins to treat gastrointestinal diseases | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2006-12-28 | — | — | US | disclosed |
| EP-1725228-A2 | USE OF DOCOSATRIENES, RESOLVINS AND THEIR STABLE ANALOGS IN THE TREATMENT OF AIRWAY DISEASES AND ASTHMA | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2006078457-A2 | USE OF RESOLVINS TO TREAT GASTROINTESTINAL DISEASES | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2006-07-27 | — | — | WO | disclosed |
| US-20050261255-A1 | Di- and tri-hydroxy derivatives of eicosapentaenoic acid and docosahexaenoic acid coadministered with a cyclooxygenase-2 inhibitor; antiinflammatory agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-11-24 | — | — | US | disclosed |
| WO-2005089744-A2 | USE OF DOCOSATRIENES, RESOLVINS AND THEIR STABLE ANALOGS IN THE TREATMENT OF AIRWAY DISEASES AND ASTHMA | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2005-09-29 | — | — | WO | disclosed |
| EP-1537067-A2 | RESOLVINS: BIOTEMPLATES FOR THERAPEUTIC INTERVENTIONS | BRIGHAM AND WOMEN'S HOSPITAL (US) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004014835-A9 | RESOLVINS: BIOTEMPLATES FOR THERAPEUTIC INTERVENTIONS | BRIGHAM & WOMENS HOSPITAL (US) | 2004-07-08 | — | — | WO | disclosed |
| US-20040116408-A1 | Resolvins: biotemplates for novel therapeutic interventions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-06-17 | — | — | US | disclosed |
| WO-2004014835-A2 | RESOLVINS: BIOTEMPLATES FOR THERAPEUTIC INTERVENTIONS | BRIGHAM AND WOMEN'S HOSPITAL (US) | 2004-02-19 | — | — | WO | disclosed |
| US-4161495-A | ADDING A FREE RADICAL SCAVENGER SELECTED FROM HYDROGEN BROMIDE, CHLORIDE, OR IODIDE, NITRIC OXIDE, AND VINYL BROMIDE | UNION CARBIDE CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |