Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 6/20 | 0.71 |
| ▸ | SLC10A1 | Q14973 | 5/20 | 0.71 |
| ▸ | SLC10A2 | Q12908 | 4/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.58 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.58 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.58 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.54 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10611231 | 0.91 | SLC10A1 (0.74) | GPBAR1SLC10A1SLC10A2TSHRRAB9A | |
| SCHEMBL10518175 | 0.89 | GPBAR1 (0.70) | GPBAR1SLC10A1SLC10A2TSHRRAB9A | |
| SCHEMBL15467238 | 0.89 | GPBAR1 (0.77) | GPBAR1SLC10A1SLC10A2TSHRRAB9A | |
| SCHEMBL25791272 | 0.89 | GPBAR1 (0.86) | GPBAR1SLC10A1SLC10A2TSHRRAB9A | |
| SCHEMBL7998870 | 0.89 | GPBAR1 (0.86) | GPBAR1SLC10A1SLC10A2TSHRRAB9A | |
| SCHEMBL23222893 | 0.89 | GPBAR1 (0.86) | GPBAR1SLC10A1SLC10A2TSHRRAB9A | |
| SCHEMBL23222871 | 0.89 | GPBAR1 (0.86) | GPBAR1SLC10A1SLC10A2TSHRRAB9A | |
| SCHEMBL15539504 | 0.87 | GPBAR1 (0.84) | GPBAR1SLC10A1SLC10A2TSHRRAB9A | |
| SCHEMBL10520272 | 0.87 | GPBAR1 (0.67) | GPBAR1SLC10A1SLC10A2LMNANR1H4 | |
| Taurocholate Sulfate SCHEMBL31402018 | 0.86 | GPBAR1 (0.81) | GPBAR1SLC10A1SLC10A2TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4810422-A | CARCINOSTATS OF LOW TOXICITY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1989-03-07 | — | — | US | disclosed |
| EP-0259185-A1 | Bile acid derivatives, their salts and production thereof | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1988-03-09 | — | — | EP | disclosed |