Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.66 |
| ▸ | CPA3 | P15088 | 3/20 | 0.66 |
| ▸ | CPA1 | P15085 | 2/20 | 0.59 |
| ▸ | CPB1 | P15086 | 1/20 | 0.59 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.59 |
| ▸ | PTGES | O14684 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.55 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.54 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.54 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.54 |
| ▸ | LAP3 | P28838 | 3/20 | 0.54 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.54 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10769990 | 1.00 | FOLH1 (0.72) | FOLH1CYP1A2GRIK1CPA3CPA1 | |
| SCHEMBL5966641 | 0.95 | FOLH1 (0.70) | FOLH1CYP1A2GRIK1CPA3CPA1 | |
| SCHEMBL27423810 | 0.95 | FOLH1 (0.70) | FOLH1CYP1A2GRIK1CPA3CPA1 | |
| SCHEMBL10521559 | 0.93 | FOLH1 (0.68) | FOLH1CYP1A2GRIK1CPA3CPA1 | |
| SCHEMBL23470222 | 0.92 | FOLH1 (0.62) | FOLH1CYP1A2GRIK1CPA3CPA1 | |
| SCHEMBL11664393 | 0.90 | FOLH1 (0.79) | FOLH1CYP1A2CPA3CPA1CPB1 | |
| SCHEMBL1856639 | 0.90 | GRIK1 (0.72) | FOLH1CYP1A2GRIK1CPA3CPA1 | |
| SCHEMBL1859177 | 0.89 | CYP1A2 (0.73) | FOLH1CYP1A2CPA3CPA1CPB1 | |
| SCHEMBL1860416 | 0.87 | GRIK1 (0.68) | FOLH1CYP1A2GRIK1CPA3CPB2 | |
| SCHEMBL19821208 | 0.86 | CYP1A2 (0.83) | FOLH1CYP1A2CPA3CPA1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863904-A | Dipeptides as renin inhibitors | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0225292-A2 | Certain N-substituted butyramide derivatives | CIBA-GEIGY AG (CH) | 1987-06-10 | — | — | EP | disclosed |
| EP-0181110-A2 | Histidine derivatives as renin inhibitors | Kissei Pharmaceutical Co. Ltd. (JP) | 1986-05-14 | — | — | EP | disclosed |