Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 7/20 | 0.76 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.76 |
| ▸ | SRC | P12931 | 2/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.76 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.76 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.76 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.76 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.72 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.72 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.72 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.72 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.68 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.68 |
| ▸ | LDHA | P00338 | 1/20 | 0.68 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.68 |
| ▸ | FBP1 | P09467 | 1/20 | 0.68 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.68 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10521997 | 0.99 | P2RY1 (0.75) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL2167542 | 0.95 | P2RY1 (0.84) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL17302811 | 0.95 | P2RY1 (0.84) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL10520556 | 0.92 | P2RY1 (0.78) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL2167549 | 0.90 | P2RY1 (0.73) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL23070936 | 0.90 | P2RY1 (0.73) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL2166391 | 0.90 | P2RY1 (0.88) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL1270476 | 0.89 | P2RY1 (0.77) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL22875605 | 0.89 | P2RY1 (0.70) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 | |
| SCHEMBL10792796 | 0.88 | P2RY1 (0.75) | P2RY1P2RY2SRCSMN1; SMN2P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4844884-A | TYROSINE DERIVATIVES AND ADENOSINE-5'-PHOSPHATES | INDUCHEM AG (CH) | 1989-07-04 | — | — | US | claimed |
| US-4844884-A | TYROSINE DERIVATIVES AND ADENOSINE-5'-PHOSPHATES | INDUCHEM AG (CH) | 1989-07-04 | — | — | US | disclosed |