Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.59 |
| ▸ | CA7 | P43166 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 9/20 | 0.46 |
| ▸ | CTSS | P25774 | 5/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365651 | 1.00 | CA1 (0.59) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL14124966 | 0.86 | CA1 (0.53) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL28966590 | 0.86 | CA1 (0.53) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL10148280 | 0.86 | CA1 (0.53) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL57872 | 0.83 | CA1 (0.55) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL69002 | 0.83 | CA1 (0.55) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL9281071 | 0.83 | CA1 (0.55) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL12666832 | 0.83 | CA1 (0.55) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL57084 | 0.83 | CA1 (0.55) | CA1CA2CA7CYP2D6CTSK | |
| SCHEMBL30070677 | 0.83 | CA1 (0.55) | CA1CA2CA7CYP2D6CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886813-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1989-12-12 | — | — | US | disclosed |