Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30002666 | 0.84 | CYP1A2 (0.46) | CNR1CNR2HTR1BKCNA3MCHR1 | |
| SCHEMBL12627506 | 0.82 | CYP2C9 (0.46) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL30003701 | 0.80 | HTR1B (0.40) | MEN1KMT2AMAPTCNR1CNR2 | |
| SCHEMBL28897589 | 0.79 | MEN1 (0.51) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL7054033 | 0.79 | MEN1 (0.51) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL20678465 | 0.79 | MEN1 (0.51) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL27782966 | 0.79 | MEN1 (0.51) | MEN1KMT2ANR1I2LMNACHRM2 | |
| Water SCHEMBL28168267 | 0.77 | MEN1 (0.50) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL12627501 | 0.77 | MEN1 (0.48) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL6742971 | 0.77 | CYP2C9 (0.45) | MEN1KMT2ANR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4843097-A | ANTITUMOR AGENTS, SKIN DISORDERS, ANTIINFLAMMATORY AGENTS | GROUPEMENT D'INTERET ECONOMIQUE DIT: CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1989-06-27 | — | — | US | claimed |