Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10522603 | 1.00 | ACE (0.56) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10522707 | 0.93 | ACE (0.57) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10522729 | 0.93 | ACE (0.57) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10520986 | 0.89 | ACE (0.50) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10520981 | 0.89 | ACE (0.50) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10384049 | 0.84 | ACE (0.55) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10384050 | 0.84 | ACE (0.55) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL905844 | 0.83 | ACE (0.80) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10610279 | 0.83 | ACE (0.60) | ACELMNASMN1; SMN2ABCB11MEN1 | |
| SCHEMBL10611042 | 0.82 | ACE (0.59) | ACELMNASMN1; SMN2ABCB11MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886813-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1989-12-12 | — | — | US | disclosed |