SCHEMBL10522604

SCHEMBL10522604

Nc1ccc(-c2c(N)c(-c3ccccc3)c(-c3ccccc3)c(-c3ccc(N)cc3)c2-c2ccc(N)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.67
TDP1 Q9NUW8 3/20 0.67
HSD17B10 Q99714 2/20 0.67
TAAR1 Q96RJ0 1/20 0.67
RAB9A P51151 5/20 0.48
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
NPC1 O15118 3/20 0.48
ALDH1A1 P00352 6/20 0.48
TP53 P04637 1/20 0.48
TSHR P16473 1/20 0.48
MAPT P10636 6/20 0.47
KDM4E B2RXH2 3/20 0.47
HPGD P15428 2/20 0.47
GLA P06280 1/20 0.47
ALOX15 P16050 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ACHE P22303 2/20 0.44
CYP1A2 P05177 3/20 0.41
CYP2C9 P11712 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39988 1.00 CYP3A4 (0.67) CYP3A4TDP1HSD17B10TAAR1RAB9A
SCHEMBL12478795 0.98 CYP3A4 (0.71) CYP3A4TDP1HSD17B10TAAR1RAB9A
SCHEMBL1720548 0.98 CYP3A4 (0.71) CYP3A4TDP1HSD17B10TAAR1RAB9A
SCHEMBL13310879 0.92 CYP3A4 (0.78) CYP3A4TDP1HSD17B10TAAR1RAB9A
SCHEMBL807664 0.92 CYP3A4 (0.78) CYP3A4TDP1HSD17B10TAAR1RAB9A
SCHEMBL20323054 0.92 CYP3A4 (0.78) CYP3A4TDP1HSD17B10TAAR1RAB9A
SCHEMBL6409531 0.89 TDP1 (0.54) CYP3A4TDP1HSD17B10TAAR1RAB9A
SCHEMBL5030574 0.89 HSD17B10 (0.48) CYP3A4TDP1HSD17B10TAAR1MEN1
SCHEMBL9330651 0.89 CYP3A4 (0.59) CYP3A4TDP1HSD17B10TAAR1RAB9A
SCHEMBL9073920 0.88 TAAR1 (0.58) CYP3A4TDP1HSD17B10TAAR1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4867529-A MULTICOMPONENT GLASS LIGHT GUIDE FIBERS AND SILICA GLASS IMAGE GUIDE ENCLOSED IN THIN-WALLED POLYIMIDE TUBE; MEDICAL DIAGNOSIS MITSUBISHI CABLE INDUSTRIES, LTD. (JP) 1989-09-19 US disclosed