Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | BCL2 | P10415 | 3/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10537061 | 0.87 | SRD5A2 (0.71) | POLBSRD5A2AKR1C3BCL2MCL1 | |
| SCHEMBL337469 | 0.85 | HPGD (0.71) | POLBSRD5A2AKR1C3KDM4EBCL2 | |
| SCHEMBL5963366 | 0.85 | POLB (1.00) | POLBSRD5A2AKR1C3KDM4EMCL1 | |
| SCHEMBL27874063 | 0.83 | POLB (0.60) | POLBSRD5A2AKR1C3BCL2MCL1 | |
| SCHEMBL234249 | 0.83 | SRD5A2 (0.84) | POLBSRD5A2AKR1C3PARP10ALDH1A1 | |
| SCHEMBL26759067 | 0.83 | SRD5A2 (0.84) | POLBSRD5A2AKR1C3PARP10ALDH1A1 | |
| SCHEMBL1069817 | 0.83 | SRD5A2 (0.84) | POLBSRD5A2AKR1C3PARP10ALDH1A1 | |
| SCHEMBL22415445 | 0.83 | SRD5A2 (0.84) | POLBSRD5A2AKR1C3PARP10ALDH1A1 | |
| SCHEMBL2868057 | 0.82 | SRD5A2 (0.70) | POLBSRD5A2AKR1C3PARP10TNKS | |
| SCHEMBL30643036 | 0.82 | SRD5A2 (0.70) | POLBSRD5A2AKR1C3PARP10TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4870153-A | MELT PROCESSABILITY, MOLDING MATERIALS | AMOCO CORPORATION (US) | 1989-09-26 | — | — | US | disclosed |