SCHEMBL10522989

SCHEMBL10522989

[CH2]CC(C)(C#N)CCCC

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13180304 0.85 TSHR (0.36) TSHR
SCHEMBL14509760 0.85 TSHR (0.36) TSHR
SCHEMBL10585928 0.83 TSHR (0.35) TSHR
SCHEMBL12808432 0.83 TSHR (0.38) TSHR
SCHEMBL366645 0.82 TSHR (0.38) TSHR
SCHEMBL27705975 0.81 TSHR (0.33) TSHR
SCHEMBL6924785 0.81 TSHR (0.33) TSHR
SCHEMBL9183342 0.81 TSHR (0.33) TSHR
Boric Acid SCHEMBL27917377 0.81 ANPEP (0.33) TSHR
SCHEMBL10029661 0.80 TSHR (0.40) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4847159-A Substrates coated with organo-silanes that are sterically-protected E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-11 US disclosed