Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 9/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PEPD | P12955 | 2/20 | 0.40 |
| ▸ | XPNPEP1 | Q9NQW7 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10523915 | 1.00 | ACE (0.52) | ACELMNASMN1; SMN2PEPDXPNPEP1 | |
| SCHEMBL10523157 | 0.99 | ACE (0.52) | ACELMNASMN1; SMN2PEPDXPNPEP1 | |
| SCHEMBL10523169 | 0.99 | ACE (0.52) | ACELMNASMN1; SMN2PEPDXPNPEP1 | |
| SCHEMBL10384148 | 0.91 | ACE (0.49) | ACELMNASMN1; SMN2PEPDXPNPEP1 | |
| SCHEMBL10384147 | 0.91 | ACE (0.49) | ACELMNASMN1; SMN2PEPDXPNPEP1 | |
| SCHEMBL10522855 | 0.91 | ACE (0.51) | ACELMNASMN1; SMN2FKBP1AABCB11 | |
| SCHEMBL10522860 | 0.91 | ACE (0.51) | ACELMNASMN1; SMN2FKBP1AABCB11 | |
| SCHEMBL10520986 | 0.91 | ACE (0.50) | ACELMNASMN1; SMN2PEPDFKBP1A | |
| SCHEMBL10520981 | 0.91 | ACE (0.50) | ACELMNASMN1; SMN2PEPDFKBP1A | |
| SCHEMBL10384057 | 0.91 | ACE (0.48) | ACELMNASMN1; SMN2PEPDXPNPEP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4886813-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1989-12-12 | — | — | US | disclosed |