Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | CA2 | P00918 | 4/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1296760 | 1.00 | CYP3A4 (0.58) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL1297165 | 0.95 | CYP3A4 (0.58) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL22856002 | 0.95 | CYP3A4 (0.53) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL1297533 | 0.94 | CYP3A4 (0.53) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL1297736 | 0.94 | CYP3A4 (0.53) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL1297715 | 0.94 | CYP3A4 (0.53) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL15071080 | 0.94 | CYP3A4 (0.53) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL1296694 | 0.94 | CYP3A4 (0.53) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL1297319 | 0.94 | CYP3A4 (0.53) | CYP3A4TSHRTDP1ATMALDH1A1 | |
| SCHEMBL25520430 | 0.94 | CYP3A4 (0.53) | CYP3A4TSHRTDP1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0222988-B1 | PROCESS FOR THE PREPARATION OF HYDROXYMETHYL PROPANE (CYCLOPROPYL METHANOL) | HÜLS AKTIENGESELLSCHAFT (DE) | 1988-08-17 | — | — | EP | claimed |
| US-4720597-A | Process for the production of hydroxymethylcyclopropane (cyclopropylmethanol) | HUELS AKTIENGESELLSCHAFT (DE) | 1988-01-19 | — | — | US | claimed |
| EP-0205403-B1 | PROCESS FOR THE MANUFACTURE OF CYCLOPROPYLAMINE | CIBA-GEIGY AG (CH) | 1989-08-30 | — | — | EP | disclosed |
| US-4778920-A | GAMMA-BUTYROLACTONE, ALCOHOL, HYDROGEN CHLORIDE YIELD GAMMA-CHLOROBUTYRIC ACID ESTER WHICH IS CYCLIZED BY ALKALI ALCOHOLATE | HUELS AKTIENGESELLSCHAFT (DE) | 1988-10-18 | — | — | US | disclosed |
| EP-0205403-A1 | Process for the manufacture of cyclopropylamine | CIBA-GEIGY AG (CH) | 1986-12-17 | — | — | EP | disclosed |
| US-4590292-A | FROM GAMMA-BUTYROLACTONE | CIBA-GEIGY CORPORATION (US) | 1986-05-20 | — | — | US | disclosed |