Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.51 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10524998 | 0.87 | CHRM2 (0.49) | CHRM2CHRM1CHRM3ATMALDH1A1 | |
| SCHEMBL5532368 | 0.75 | CHRM1 (0.59) | CHRM2CHRM1CHRM3ATMALDH1A1 | |
| SCHEMBL10522120 | 0.74 | CHRM2 (0.45) | CHRM2CHRM1CHRM3ATMALDH1A1 | |
| Hydrochloric Acid SCHEMBL10391348 | 0.71 | CYP2D6 (0.53) | CHRM2CHRM1CHRM3ALDH1A1KMT2A | |
| SCHEMBL2596509 | 0.70 | HDAC3 (0.61) | CHRM2CHRM1ATMKMT2AMEN1 | |
| Trantelinium SCHEMBL29385462 | 0.68 | APOBEC3A (0.53) | CHRM2CHRM1CHRM3ATMALDH1A1 | |
| SCHEMBL3574604 | 0.68 | CHRM3 (1.00) | CHRM2CHRM1CHRM3ALDH1A1KDM4E | |
| SCHEMBL7200244 | 0.68 | CHRM3 (1.00) | CHRM2CHRM1CHRM3ALDH1A1KDM4E | |
| SCHEMBL13875521 | 0.65 | CHRM3 (0.59) | CHRM2CHRM1CHRM3ATMALDH1A1 | |
| SCHEMBL4184283 | 0.64 | CHRM3 (0.55) | CHRM2CHRM1CHRM3ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0309422-A2 | New amidino tricycle derivatives | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-03-29 | — | — | EP | disclosed |