Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 2/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | MDH1 | P40925 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10527124 | 0.99 | RARB (0.45) | RARBMAPTSMN1; SMN2RARARARG | |
| SCHEMBL10525381 | 0.99 | RARB (0.45) | RARBMAPTSMN1; SMN2RARARARG | |
| SCHEMBL10527674 | 0.99 | RARB (0.45) | RARBMAPTSMN1; SMN2RARARARG | |
| SCHEMBL10525451 | 0.99 | RARB (0.45) | RARBMAPTSMN1; SMN2RARARARG | |
| SCHEMBL10526711 | 0.99 | RARB (0.45) | RARBMAPTSMN1; SMN2RARARARG | |
| SCHEMBL10526443 | 0.99 | RARB (0.45) | RARBMAPTSMN1; SMN2RARARARG | |
| SCHEMBL10526629 | 0.99 | RARB (0.45) | RARBMAPTSMN1; SMN2RARARARG | |
| SCHEMBL10526494 | 0.99 | RARB (0.45) | RARBMAPTSMN1; SMN2RARARARG | |
| SCHEMBL10524527 | 0.99 | RARB (0.45) | RARBMAPTSMN1; SMN2RARARARG | |
| SCHEMBL10523844 | 0.90 | NPC1 (0.45) | RARBMAPTSMN1; SMN2RARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4871472-A | Esters in ferroelectric mixtures | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-10-03 | — | — | US | disclosed |
| EP-0258340-A1 | SMECTIC LIQUID CRYSTAL PHASES | MERCK PATENT GmbH (DE) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987005013-A2 | SMECTIC LIQUID CRYSTAL PHASES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-08-27 | — | — | WO | disclosed |