Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.73 |
| ▸ | CNR1 | P21554 | 1/20 | 0.73 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.73 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.72 |
| ▸ | FAP | Q12884 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
| ▸ | APEX1 | P27695 | 3/20 | 0.63 |
| ▸ | APAF1 | O14727 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.63 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.63 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.63 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526986 | 1.00 | TDP1 (0.73) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9481601 | 0.93 | PTGS1 (0.83) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9481608 | 0.93 | PTGS1 (0.83) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10490308 | 0.92 | MAPT (0.71) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10813924 | 0.92 | MAPT (0.71) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10490304 | 0.92 | MAPT (0.71) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10490090 | 0.92 | MAPT (0.71) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10490089 | 0.92 | MAPT (0.71) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10813918 | 0.92 | MAPT (0.71) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9482824 | 0.92 | PTGS1 (0.72) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105459-B1 | SYN-ISOMER OF 7-SUBSTITUTED-3-VINYL-3-CEPHEM COMPOUNDS, PROCESSES FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-22 | — | — | EP | claimed |
| US-4559334-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-17 | — | — | US | claimed |
| EP-0105459-A2 | Syn-isomer of 7-substituted-3-vinyl-3-cephem compounds, processes for production thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-04-18 | — | — | EP | claimed |
| EP-0105459-B1 | SYN-ISOMER OF 7-SUBSTITUTED-3-VINYL-3-CEPHEM COMPOUNDS, PROCESSES FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-03-22 | — | — | EP | disclosed |
| US-4559334-A | MICROBIOCIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-17 | — | — | US | disclosed |
| EP-0105459-A2 | Syn-isomer of 7-substituted-3-vinyl-3-cephem compounds, processes for production thereof and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-04-18 | — | — | EP | disclosed |