Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | F7 | P08709 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 6/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17967674 | 0.73 | PDE5A (0.41) | F2F10F7F3IDO1 | |
| SCHEMBL7377865 | 0.67 | ACVR1 (0.55) | ACVR1 | |
| SCHEMBL10525022 | 0.64 | PARP1 (0.44) | HCAR2AXLNUDT1 | |
| SCHEMBL9671708 | 0.64 | NR4A2 (0.42) | GSK3BAXLNUDT1ACVR1 | |
| SCHEMBL5891633 | 0.64 | DAO (0.47) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL2693525 | 0.62 | HCAR2 (0.42) | F2F10F7F3IDO1 | |
| SCHEMBL8967704 | 0.62 | CYP3A4 (0.46) | F2F10F7F3IDO1 | |
| SCHEMBL11299370 | 0.62 | KDM4E (0.42) | F2F10F7F3IDO1 | |
| SCHEMBL1710995 | 0.61 | NPC1 (0.45) | TDP2NSD2ABL1PLCG1CES1 | |
| SCHEMBL8600442 | 0.61 | AXL (0.46) | HCAR2AXLNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4801590-A | ANGINA, ANTICANCER, CARDIOVASCULAR DISORDERS, HEADACHES, PSORIASIS, ASTHMA, ANTICOAGULANTS | BEIERSDORF AG (DE) | 1989-01-31 | — | — | US | disclosed |
| EP-0253171-A1 | Pyrido[1,8]naphthyridinones, process for their preparation and their use and compositions containing them | Beiersdorf-Lilly GmbH (DE) | 1988-01-20 | — | — | EP | disclosed |