Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | FAP | Q12884 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.56 |
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10797134 | 1.00 | TDP1 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10490271 | 1.00 | TDP1 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10490266 | 1.00 | TDP1 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10795144 | 0.95 | MAPT (0.67) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10490364 | 0.95 | MAPT (0.67) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10529456 | 0.95 | MAPT (0.67) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10490381 | 0.95 | MAPT (0.67) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10490376 | 0.95 | MAPT (0.67) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10490107 | 0.95 | MAPT (0.67) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10490106 | 0.95 | MAPT (0.67) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4708955-A | ANTIBACTERIALS | BRISTOL-MYERS COMPANY (US) | 1987-11-24 | — | — | US | claimed |
| EP-0304036-A2 | 3-(substituted)propenyl-7-(aminothiazolylacetamido)ceph-3-em-4-carboxylic acids and esters thereof | Bristol-Myers Squibb Company (US) | 1989-02-22 | — | — | EP | disclosed |
| US-4708955-A | ANTIBACTERIALS | BRISTOL-MYERS COMPANY (US) | 1987-11-24 | — | — | US | disclosed |