Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271616 | 0.84 | — | — | |
| SCHEMBL20610005 | 0.78 | TSHR (0.59) | TSHRACE2FDPS | |
| SCHEMBL28841264 | 0.76 | TSHR (0.46) | TSHRACE2FDPS | |
| SCHEMBL9630991 | 0.75 | ACE2 (0.47) | ACE2FDPS | |
| SCHEMBL56451 | 0.74 | — | — | |
| SCHEMBL9368619 | 0.74 | — | — | |
| SCHEMBL270381 | 0.74 | — | — | |
| SCHEMBL6141164 | 0.73 | — | — | |
| SCHEMBL277789 | 0.72 | — | — | |
| SCHEMBL1410786 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4804742-A | OSTEOPOROSIS TREATMENT OF EXTENDED DURATION | RORER PHARMACEUTICAL CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| US-4650854-A | OSTEOPOROSIS | USV PHARMACEUTICAL CORPORATION (US) | 1987-03-17 | — | — | US | disclosed |